HSPMdb Accession NoHSPMDB001860
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name129
IUPAC NameBenzyl (1-(Bis(4-acetamidophenoxy)phosphoryl)-2-(4-(trifluoromethyl)phenyl)ethyl)carbamate
SMILESO=C(OC(P(OC1=CC=C(NC(C)=O)C=C1)(OC2=CC=C(NC(C)=O)C=C2)=O)CC3=CC=C(C(F)(F)F)C=C3)NCC4=CC=CC=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change1% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001860

129

Physicochemical Properties