HSPMdb Accession NoHSPMDB001859
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name128
IUPAC NameMethyl ((Diphenoxyphosphoryl)(3-(trifluoromethyl)phenyl)-methyl)carbamate
SMILESO=C(OC)NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3=CC=CC(C(F)(F)F)=C3
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change4% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001859

128

Physicochemical Properties