HSPMdb Accession NoHSPMDB001858
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name127
IUPAC NameBenzyl ((4-(Dimethylamino)-3-(methylsulfonamido)phenyl)-(diphenoxyphosphoryl)methyl)carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(C2=CC=C(N(C)C)C(NS(=O)(C)=O)=C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change46% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001858

127

Physicochemical Properties