HSPMdb Accession No | HSPMDB001856 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 125 |
IUPAC Name | Benzyl ((Diphenoxyphosphoryl)(5-guanidinonaphthalen-1-yl)-methyl)carbamate 2,2,2-trifluoroacetate |
SMILES | O=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=C5C=CC=C(NC(N)=N)C5=CC=C4.O=C(O)C(F)(F)F |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 38% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |