HSPMdb Accession NoHSPMDB001850
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name118
IUPAC NameB e n z y l ( ( 4 - ( D i m e t h y l a m i n o ) - 3 - n i t r o p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(C2=CC=C(N(C)C)C([N+]([O-])=O)=C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change39% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001850

118

Physicochemical Properties