HSPMdb Accession NoHSPMDB001849
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name117
IUPAC NameBenzyl ((Diphenoxyphosphoryl)(5-nitronaphthalen-1-yl)methyl)-carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=C5C=CC=C([N+]([O-])=O)C5=CC=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change49% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001849

117

Physicochemical Properties