| HSPMdb Accession No | HSPMDB001847 |
| PMID | 30571121 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of peptidase activity |
| Compound Name | 115 |
| IUPAC Name | Benzyl ((1-Carbamimidoylazetidin-3-yl)(diphenoxyphosphoryl)-methyl)carbamate 2,2,2-trifluoroacetate |
| SMILES | O=C(OCC1=CC=CC=C1)NC(C2CN(C(N)=N)C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O.O=C(O)C(F)(F)F |
| Class | Serine protease inhibitor library |
| % Enzymatic Inhibition/Fold Change | 100% at 200 uM |
| IC50 (µM) | 71.3 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Disease | Bacterial infection |
Loading Please Wait ...