HSPMdb Accession NoHSPMDB001845
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name111
IUPAC NameBenzyl ((4-(Aminomethyl)cyclohexyl)(diphenoxyphosphoryl)-methyl)carbamate 2,2,2-Trifluoroacetate
SMILESO=C(OCC1=CC=CC=C1)NC(C2CCC(CN)CC2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change15% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001845

111

Physicochemical Properties