HSPMdb Accession NoHSPMDB001844
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name110
IUPAC NameBenzyl 1-(Diphenoxyphosphoryl)-2-(piperidin-4-yl)-ethylcarbamate 2,2,2-Trifluoroacetate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4CCNCC4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change16% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001844

110

Physicochemical Properties