| HSPMdb Accession No | HSPMDB001842 |
| PMID | 30571121 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of peptidase activity |
| Compound Name | 108 |
| IUPAC Name | B e n z y l ( ( 3 - C y a n o - 4 - ( p i p e r a z i n - 1 - y l ) p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate 2,2,2-trifluoroacetate |
| SMILES | O=C(OCC1=CC=CC=C1)NC(C2=CC=C(N3CCNCC3)C(C#N)=C2)P(OC4=CC=CC=C4)(OC5=CC=CC=C5)=O.O=C(O)C(F)(F)F |
| Class | Serine protease inhibitor library |
| % Enzymatic Inhibition/Fold Change | 10% at 200 uM |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Disease | Bacterial infection |
Loading Please Wait ...