HSPMdb Accession NoHSPMDB001840
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name98
IUPAC NameBenzyl ((Diphenoxyphosphoryl)(4-(2,2,2-trifluoroacetamido)-phenyl)methyl)carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=CC=C(NC(C(F)(F)F)=O)C=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change15% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001840

98

Physicochemical Properties