HSPMdb Accession NoHSPMDB001828
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name86
IUPAC NameBenzyl ((Diphenoxyphosphoryl)(6-methoxypyridin-2-yl)methyl)-carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=NC(OC)=CC=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change100% at 200 uM
IC50 (µM)38
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001828

86

Physicochemical Properties