HSPMdb Accession NoHSPMDB001820
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name78
IUPAC NameBenzyl ((4-(Dimethylamino)phenyl)(diphenoxyphosphoryl)-methyl)carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(C2=CC=C(N(C)C)C=C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change100% at 200 uM
IC50 (µM)0.6
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001820

78

Physicochemical Properties