HSPMdb Accession NoHSPMDB001816
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name74
IUPAC NameDiphenyl ((3-(N-Hydroxycarbamimidoyl)phenyl)(pyrimidin-2-ylamino)methyl)phosphonate
SMILESN=C(C1=CC(C(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)NC4=NC=CC=N4)=CC=C1)NO
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change23% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001816

74

Physicochemical Properties