HSPMdb Accession NoHSPMDB001815
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name73
IUPAC NameDiphenyl ((1-Carbamimidoylazetidin-3-yl)(pyrimidin-2-ylamino)methyl)phosphonate 2,2,2-trifluoroacetate
SMILESNC(N1CC(C(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)NC4=NC=CC=N4)C1)=N.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change12% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001815

73

Physicochemical Properties