HSPMdb Accession NoHSPMDB001813
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name71
IUPAC NameMethyl ((4-Carbamimidoylphenyl)(diphenoxyphosphoryl)-methyl)carbamate
SMILESO=C(OC)NC(C1=CC=C(C(N)=N)C=C1)P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change93% at 200 uM
IC50 (µM)48.1
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001813

71

Physicochemical Properties