HSPMdb Accession No | HSPMDB001813 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 71 |
IUPAC Name | Methyl ((4-Carbamimidoylphenyl)(diphenoxyphosphoryl)-methyl)carbamate |
SMILES | O=C(OC)NC(C1=CC=C(C(N)=N)C=C1)P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 93% at 200 uM |
IC50 (µM) | 48.1 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |