HSPMdb Accession NoHSPMDB001812
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name70
IUPAC NameBenzyl (1-(Diphenoxyphosphoryl)-3-(4-nitrophenyl)propyl)-carbamate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CCC4=CC=C([N+]([O-])=O)C=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change100% at 200 uM
IC50 (µM)13.1
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001812

70

Physicochemical Properties