HSPMdb Accession No | HSPMDB001812 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 70 |
IUPAC Name | Benzyl (1-(Diphenoxyphosphoryl)-3-(4-nitrophenyl)propyl)-carbamate |
SMILES | O=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CCC4=CC=C([N+]([O-])=O)C=C4 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 100% at 200 uM |
IC50 (µM) | 13.1 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |