HSPMdb Accession No | HSPMDB001810 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 68 |
IUPAC Name | B e n z y l 2 - ( 4 - ( 3 , 3 - D i m e t h y l u r e i d o ) p h e n y l ) - 1 -(diphenoxyphosphoryl)ethylcarbamate |
SMILES | O=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(NC(N(C)C)=O)C=C4 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 9% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |