HSPMdb Accession NoHSPMDB001810
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name68
IUPAC NameB e n z y l 2 - ( 4 - ( 3 , 3 - D i m e t h y l u r e i d o ) p h e n y l ) - 1 -(diphenoxyphosphoryl)ethylcarbamate
SMILESO=C(OCC1=CC=CC=C1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(NC(N(C)C)=O)C=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change9% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001810

68

Physicochemical Properties