HSPMdb Accession No | HSPMDB001809 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 67 |
IUPAC Name | 2-Ami n o e t h y l ((Diphenoxyphosph o r y l ) ( 4 - ( 2 , 2 , 2 -trifluoroacetamido)phenyl)methyl)carbamate 2,2,2-Trifluoroacetate |
SMILES | O=C(OCCN)NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3=CC=C(NC(C(F)(F)F)=O)C=C3.O=C(O)C(F)(F)F |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 73% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |