HSPMdb Accession NoHSPMDB001809
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name67
IUPAC Name2-Ami n o e t h y l ((Diphenoxyphosph o r y l ) ( 4 - ( 2 , 2 , 2 -trifluoroacetamido)phenyl)methyl)carbamate 2,2,2-Trifluoroacetate
SMILESO=C(OCCN)NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3=CC=C(NC(C(F)(F)F)=O)C=C3.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change73% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001809

67

Physicochemical Properties