| HSPMdb Accession No | HSPMDB001808 |
| PMID | 30571121 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of peptidase activity |
| Compound Name | 66 |
| IUPAC Name | Benzo[d][1,3]dioxol-5-ylmethyl ((Diphenoxyphosphoryl)(4-(2,2,2-trifluoroacetamido)phenyl)methyl)carbamate |
| SMILES | O=C(OCC1=CC=C(OCO2)C2=C1)NC(P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O)C5=CC=C(NC(C(F)(F)F)=O)C=C5 |
| Class | Serine protease inhibitor library |
| % Enzymatic Inhibition/Fold Change | 93% at 200 uM |
| IC50 (µM) | 8.2 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Disease | Bacterial infection |
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