HSPMdb Accession NoHSPMDB001806
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name64
IUPAC Name(Perfluorophenyl)methyl ((Diphenoxyphosphoryl)(4-guanidinophenyl)methyl)carbamate
SMILESO=C(OCC1=C(F)C(F)=C(F)C(F)=C1F)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4=CC=C(NC(N)=N)C=C4
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change48% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001806

64

Physicochemical Properties