HSPMdb Accession NoHSPMDB001805
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name63
IUPAC NameDiphenyl ((4-Guanidinophenyl)(phenylsulfonamido)methyl)-phosphonate
SMILESO=S(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3=CC=C(NC(N)=N)C=C3)(C4=CC=CC=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change29% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001805

63

Physicochemical Properties