HSPMdb Accession No | HSPMDB001804 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 62 |
IUPAC Name | Diphenyl ((4-Guanidinophenyl)((4-(trifluoromethyl)phenyl)-sulfonamido)methyl)phosphonate |
SMILES | O=S(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3=CC=C(NC(N)=N)C=C3)(C4=CC=C(C(F)(F)F)C=C4)=O |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 27% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |