HSPMdb Accession No | HSPMDB001803 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 61 |
IUPAC Name | ( P e r fl u o r o p h e n y l ) m e t h y l ( ( 4 - A m i n o p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate |
SMILES | O=C(OCC1=C(F)C(F)=C(F)C(F)=C1F)NC(C2=CC=C(N)C=C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 28% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |