HSPMdb Accession NoHSPMDB001803
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name61
IUPAC Name( P e r fl u o r o p h e n y l ) m e t h y l ( ( 4 - A m i n o p h e n y l ) -(diphenoxyphosphoryl)methyl)carbamate
SMILESO=C(OCC1=C(F)C(F)=C(F)C(F)=C1F)NC(C2=CC=C(N)C=C2)P(OC3=CC=CC=C3)(OC4=CC=CC=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change28% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001803

61

Physicochemical Properties