HSPMdb Accession NoHSPMDB001802
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name60
IUPAC Name4,4,4-Trifluorobutyl ((4-Aminophenyl)(diphenoxyphosphoryl)-methyl)carbamate
SMILESO=C(OCCCC(F)(F)F)NC(C1=CC=C(N)C=C1)P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change<1% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001802

60

Physicochemical Properties