HSPMdb Accession No | HSPMDB001798 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 56 |
IUPAC Name | (Perfluorophenyl)methyl (1-(Diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethyl)carbamate 2,2,2-Trifluoroacetate |
SMILES | O=C(OCC1=C(F)C(F)=C(F)C(F)=C1F)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(NC(N)=N)C=C4 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 25% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |