HSPMdb Accession No | HSPMDB001797 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 55 |
IUPAC Name | 2-(2-Azidoethoxy)ethyl (1-(diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethyl)carbamate |
SMILES | O=C(OCCOCCN=[N+]=[N-])NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)CC3=CC=C(NC(N)=N)C=C3 |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 68% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |