HSPMdb Accession NoHSPMDB001797
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name55
IUPAC Name2-(2-Azidoethoxy)ethyl (1-(diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethyl)carbamate
SMILESO=C(OCCOCCN=[N+]=[N-])NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)CC3=CC=C(NC(N)=N)C=C3
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change68% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001797

55

Physicochemical Properties