| HSPMdb Accession No | HSPMDB001795 |
| PMID | 30571121 |
| Target | Hsp100 |
| HSP Name | ClpP |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of peptidase activity |
| Compound Name | 53 |
| IUPAC Name | Diphenyl (2-(4-Guanidinophenyl)-1-((S)-2-((S)-3-hydroxy-2-(thiophene-2-carboxamido)propanamido)propanamido)ethyl)-phosphonate |
| SMILES | C[C@H](NC([C@@H](NC(C1=CC=CS1)=O)CO)=O)C(NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(NC(N)=N)C=C4)=O |
| Class | Serine protease inhibitor library |
| % Enzymatic Inhibition/Fold Change | 90% at 200 uM |
| IC50 (µM) | 49.5 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
| Disease | Bacterial infection |
Loading Please Wait ...