HSPMdb Accession NoHSPMDB001794
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name52
IUPAC NameMethyl (1-(Diphenoxyphosphoryl)-2-(4-guanidinophenyl)ethyl)-carbamate
SMILESO=C(OC)NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)CC3=CC=C(NC(N)=N)C=C3
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change27% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001794

52

Physicochemical Properties