HSPMdb Accession NoHSPMDB001793
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name51
IUPAC Name(Z)-Diphenyl ((1-Carbamimidoylpiperidin - 4 - y l ) ( 3 -phenylacrylamido)methyl)phosphonate 2,2,2-Trifluoroacetate
SMILESO=C(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3CCN(C(N)=N)CC3)/C=C\C4=CC=CC=C4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change11% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001793

51

Physicochemical Properties