HSPMdb Accession NoHSPMDB001791
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name49
IUPAC NameDiphenyl ((3-(Benzo[d][1,3]dioxol-5-yl)propiolamido)(1-carbamimidoylpiperidin-4-yl)methyl)phosphonate
SMILESNC(N1CCC(C(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)NC(C#CC4=CC=C(OCO5)C5=C4)=O)CC1)=N
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change24% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001791

49

Physicochemical Properties