HSPMdb Accession NoHSPMDB001787
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name45
IUPAC NameDiphenyl ((1-Carbamimidoylpiperidin-4-yl)(cinnamamido)-methyl)phosphonate Bis(2,2,2-trifluoroacetate)
SMILESO=C(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3CCN(C(N)=N)CC3)/C=C/C4=CC=CC=C4.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change18% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001787

45

Physicochemical Properties