HSPMdb Accession NoHSPMDB001786
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name44
IUPAC NameDiphenyl ((1-Carbamimidoylpiperidin-4-yl)(furan-2-carboxamido)methyl)phosphonate 2,2,2-trifluoroacetate
SMILESO=C(C1=CC=CO1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4CCN(C(N)=N)CC4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change24% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001786

44

Physicochemical Properties