HSPMdb Accession No | HSPMDB001786 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 44 |
IUPAC Name | Diphenyl ((1-Carbamimidoylpiperidin-4-yl)(furan-2-carboxamido)methyl)phosphonate 2,2,2-trifluoroacetate |
SMILES | O=C(C1=CC=CO1)NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)C4CCN(C(N)=N)CC4.O=C(O)C(F)(F)F |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 24% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |