HSPMdb Accession NoHSPMDB001784
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name42
IUPAC NameDiphenyl ((1-Carbamimidoy l p i p e r i d i n - 4 - y l ) ( 2 - ( 4 -methoxyphenyl)acetamido)methyl)phosphonate 2,2,2-trifluoroacetate
SMILESO=C(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3CCN(C(N)=N)CC3)CC4=CC=C(OC)C=C4.O=C(O)C(F)(F)F
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change13% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001784

42

Physicochemical Properties