HSPMdb Accession No | HSPMDB001784 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 42 |
IUPAC Name | Diphenyl ((1-Carbamimidoy l p i p e r i d i n - 4 - y l ) ( 2 - ( 4 -methoxyphenyl)acetamido)methyl)phosphonate 2,2,2-trifluoroacetate |
SMILES | O=C(NC(P(OC1=CC=CC=C1)(OC2=CC=CC=C2)=O)C3CCN(C(N)=N)CC3)CC4=CC=C(OC)C=C4.O=C(O)C(F)(F)F |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | 13% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |