HSPMdb Accession NoHSPMDB001783
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name41
IUPAC NameBenzyl ((S)-1-(((S)-1-Cyano-2-(4-hydroxyphenyl)ethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate
SMILESO=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(N[C@H](C#N)CC2=CC=C(O)C=C2)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change13% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001783

41

Physicochemical Properties