HSPMdb Accession NoHSPMDB001782
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name36
IUPAC NameBenzyl ((2S)-6-Amino-1-((1-(diphenoxyphosphoryl)-3-(methylthio)propyl)amino)-1-oxohexan-2-yl)carbamate Hydrochloride
SMILESO=C(OCC1=CC=CC=C1)N[C@@H](CCCCN)C(NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CCSC)=O.[H]Cl
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change4% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001782

36

Physicochemical Properties