HSPMdb Accession No | HSPMDB001781 |
PMID | 30571121 |
Target | Hsp100 |
HSP Name | ClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | 32 |
IUPAC Name | Benzyl ((2S)-1-((1-(Diphenoxyphosphoryl)-2-(4-hydroxyphenyl)-ethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate |
SMILES | O=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4)=O |
Class | Serine protease inhibitor library |
% Enzymatic Inhibition/Fold Change | <1% at 200 uM |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |