HSPMdb Accession NoHSPMDB001781
PMID30571121
TargetHsp100
HSP NameClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound Name32
IUPAC NameBenzyl ((2S)-1-((1-(Diphenoxyphosphoryl)-2-(4-hydroxyphenyl)-ethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamate
SMILESO=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(NC(P(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4)=O
ClassSerine protease inhibitor library
% Enzymatic Inhibition/Fold Change<1% at 200 uM
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001781

32

Physicochemical Properties