HSPMdb Accession No | HSPMDB001757 |
PMID | 30109319 |
Target | Hsp100 |
HSP Name | hClpP |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of peptidase activity |
Compound Name | AV167 |
IUPAC Name | 4-(1,3,4-oxadiazol-2-yl)phenyl 2-{naphtho[2,1-b]furan-1-yl}acetate |
SMILES | O=C(CC1=COC2=C1C1=C(C=CC=C1)C=C2)OC1=CC=C(C=C1)C1=NN=CO1 |
Class | Naphthofuran derivative with 8-methoxynaphthofuran moiety |
IC50 (µM) | 1.44 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Peptidase assay (SLY-AMC) |
Disease | Bacterial infection |