HSPMdb Accession NoHSPMDB001757
PMID30109319
TargetHsp100
HSP NamehClpP
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of peptidase activity
Compound NameAV167
IUPAC Name4-(1,3,4-oxadiazol-2-yl)phenyl 2-{naphtho[2,1-b]furan-1-yl}acetate
SMILESO=C(CC1=COC2=C1C1=C(C=CC=C1)C=C2)OC1=CC=C(C=C1)C1=NN=CO1
ClassNaphthofuran derivative with 8-methoxynaphthofuran moiety
IC50 (µM)1.44
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)
DiseaseBacterial infection

Structure



HSPMDB001757

AV167

Physicochemical Properties