HSPMdb Accession NoHSPMDB001752
PMID30109319
TargetHsp100
HSP NamehClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of peptidase activity
Compound NameTG42
IUPAC Name4-(1,3,4-Oxadiazol-2-yl)phenyl 2-(2-ethynylnaphtho[2,1-b]furan-1-yl)acetate
SMILESO=C(Cc1c(oc2ccc3ccccc3c12)C#C)Oc4ccc(cc4)c5ocnn5
ClassNaphthofuran derivative with 8-methoxynaphthofuran moiety
IC50 (µM)0.39
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB001752

TG42

Physicochemical Properties