HSPMdb Accession NoHSPMDB001750
PMID30109319
TargetHsp100
HSP NamehClpP
OrganismHuman
LocalizationMitochondria
Enzymatic activityInhibition of peptidase activity
Compound NameD3
IUPAC Name3-(non-8-en-1-yl)-4-(pent-4-yn-1-yl)oxetan-2-one
SMILESC=CCCCCCCCC1C(CCCC#C)OC1=O
ClassNaphthofuran derivative with 8-methoxynaphthofuran moiety
IC50 (µM)6.99
Site of InteractionNucleotide binding domain
Type of Enzymatic AssayPeptidase assay (SLY-AMC)

Structure



HSPMDB001750

D3

Physicochemical Properties