| HSPMdb Accession No | HSPMDB001664 |
| PMID | 28906057 |
| Target | Hsp100 |
| HSP Name | ClpX |
| Organism | Bacteria |
| Localization | Cytosol |
| Enzymatic activity | Inhibition of protease activity |
| Compound Name | 375 |
| IUPAC Name | N-{2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethyl}-2-(3-methoxyphenyl)-17-oxo-2?³-thia-9-azatetracyclo[8.7.0.0³,?.0¹¹,¹?]heptadeca-1(10),3(8),4,6,11,13,15-heptaene-14-carboxamide |
| SMILES | [H]C1=C(C=C2C(=O)C3=C(NC4=C(C=CC=C4)[S]3C3=CC=CC(OC)=C3)C2=C1)C(=O)NCCC1(CCC#C)N=N1 |
| Class | Synthetic chemical compounds |
| IC50 (µM) | <50 |
| Site of Interaction | Nucleotide binding domain |
| Type of Enzymatic Assay | Substrate degradation assay (GFP) |
| Disease | Bacterial infection |
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