HSPMdb Accession NoHSPMDB001663
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name365
IUPAC Name11-([1,1'-biphenyl]-4-yl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one
SMILESO=C1c2ccccc2C3=C1C(Sc4ccccc4N3)c5ccc(cc5)c6ccccc6
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001663

365

Physicochemical Properties