HSPMdb Accession No | HSPMDB001663 |
PMID | 28906057 |
Target | Hsp100 |
HSP Name | ClpX |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 365 |
IUPAC Name | 11-([1,1'-biphenyl]-4-yl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one |
SMILES | O=C1c2ccccc2C3=C1C(Sc4ccccc4N3)c5ccc(cc5)c6ccccc6 |
Class | Synthetic chemical compounds |
IC50 (µM) | <50 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (GFP) |
Disease | Bacterial infection |