HSPMdb Accession No | HSPMDB001661 |
PMID | 28906057 |
Target | Hsp100 |
HSP Name | ClpX |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 364 |
IUPAC Name | 11-(4-(trifluoromethyl)phenyl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one 10,10-dioxide |
SMILES | FC(F)(F)c1ccc(cc1)C2C3=C(Nc4ccccc4[S]2(=O)=O)c5ccccc5C3=O |
Class | Synthetic chemical compounds |
IC50 (µM) | <50 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (GFP) |
Disease | Bacterial infection |