HSPMdb Accession NoHSPMDB001660
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name362
IUPAC Name11-(3-methoxyphenyl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one 10,10- dioxide
SMILESCOc1cccc(c1)C2C3=C(Nc4ccccc4[S]2(=O)=O)c5ccccc5C3=O
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001660

362

Physicochemical Properties