HSPMdb Accession NoHSPMDB001659
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name374
IUPAC NameN-{2-[3-(but-3-yn-1-yl)-3H-diazirin-3-yl]ethyl}-2-(3-methoxyphenyl)-17-oxo-2?³-thia-9-azatetracyclo[8.7.0.0³,?.0¹¹,¹?]heptadeca-1(10),3(8),4,6,11,13,15-heptaene-14-carboxamide
SMILES[H]C1=C(C=C2C(=O)C3=C(NC4=C(C=CC=C4)[S]3C3=CC=CC(OC)=C3)C2=C1)C(=O)NCCC1(CCC#C)N=N1
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001659

374

Physicochemical Properties