HSPMdb Accession NoHSPMDB001658
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name354
IUPAC Name11-(4-fluorophenyl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one 10,10-dioxide
SMILESFc1ccc(cc1)C2C3=C(Nc4ccccc4[S]2(=O)=O)c5ccccc5C3=O
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001658

354

Physicochemical Properties