HSPMdb Accession NoHSPMDB001657
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name360
IUPAC Name11-(4-(trifluoromethyl)phenyl)-5H-benzo[b]indeno[1,2-e][1,4]thiazepin-12(11H)-one
SMILESFC(F)(F)c1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001657

360

Physicochemical Properties