HSPMdb Accession NoHSPMDB001654
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name345
IUPAC Name5,11-Dihydro-11-(3-hydroxyphenyl)-8-methoxy-12H-benzo[b]indeno[1,2- e][1,4]thiazepin-12-one
SMILESCOc1ccc2NC3=C(C(Sc2c1)c4cccc(O)c4)C(=O)c5ccccc35
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001654

345

Physicochemical Properties