HSPMdb Accession No | HSPMDB001654 |
PMID | 28906057 |
Target | Hsp100 |
HSP Name | ClpX |
Organism | Bacteria |
Localization | Cytosol |
Enzymatic activity | Inhibition of protease activity |
Compound Name | 345 |
IUPAC Name | 5,11-Dihydro-11-(3-hydroxyphenyl)-8-methoxy-12H-benzo[b]indeno[1,2- e][1,4]thiazepin-12-one |
SMILES | COc1ccc2NC3=C(C(Sc2c1)c4cccc(O)c4)C(=O)c5ccccc35 |
Class | Synthetic chemical compounds |
IC50 (µM) | <50 |
Site of Interaction | Nucleotide binding domain |
Type of Enzymatic Assay | Substrate degradation assay (GFP) |
Disease | Bacterial infection |