HSPMdb Accession NoHSPMDB001649
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name370
IUPAC Name2-(3-hydroxyphenyl)-17-oxo-N-(prop-2-yn-1-yl)-2?³-thia-9-azatetracyclo[8.7.0.0³,?.0¹¹,¹?]heptadeca-1(10),3(8),4,6,11,13,15-heptaene-13-carboxamide
SMILESOC=1C=C(C=CC1)[S]1C=2C(C3=CC=C(C=C3C2NC=2C=CC=CC12)C(=O)NCC#C)=O
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001649

370

Physicochemical Properties