HSPMdb Accession NoHSPMDB001645
PMID28906057
TargetHsp100
HSP NameClpX
OrganismBacteria
LocalizationCytosol
Enzymatic activityInhibition of protease activity
Compound Name343
IUPAC Name5,11-Dihydro-11-(4-hydroxyphenyl)-12H-benzo[b]indeno[1,2-e][1,4]thiazepin-12-one
SMILESOc1ccc(cc1)C2Sc3ccccc3NC4=C2C(=O)c5ccccc45
ClassSynthetic chemical compounds
IC50 (µM)<50
Site of InteractionNucleotide binding domain
Type of Enzymatic AssaySubstrate degradation assay (GFP)
DiseaseBacterial infection

Structure



HSPMDB001645

343

Physicochemical Properties